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Updated: Oct 3, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
A computational framework to solve the nonlinear dengue fever SIR system.
Muhammad Umar1, Kusen2, Muhammad Asif Zahoor Raja3
1Department of Mathematics and Statistics, Hazara University, Mansehra, Pakistan.
Artificial neural networks with Levenberg-Marquardt backpropagation (ANNs-LMB) accurately model the nonlinear dengue fever SIR system. This method offers a reliable approach for predicting disease dynamics.
Area of Science:
- Mathematical modeling
- Epidemiology
- Computational intelligence
Background:
- Dengue fever poses a significant global health challenge, necessitating accurate predictive models.
- The Susceptible-Infected-Recovered (SIR) model is a fundamental epidemiological tool.
- Nonlinear dynamics in SIR models require advanced numerical techniques for accurate simulation.
Purpose of the Study:
- To present a numerical solution for the nonlinear dengue fever SIR system.
- To apply artificial neural networks with Levenberg-Marquardt backpropagation (ANNs-LMB) for this purpose.
- To evaluate the accuracy and reliability of the proposed ANNs-LMB method.
Main Methods:
- The ANNs-LMB technique was employed for numerical simulation.
- Data was partitioned into training (75%), validation (15%), and testing (10%) sets.
- A reference dataset was generated using the Adams scheme for comparison.
Main Results:
- The ANNs-LMB method successfully reduced the mean squared error in predicting dengue fever dynamics.
- The model demonstrated high accuracy, reliability, and effectiveness.
- Performance was validated through fitness landscapes, correlation, error histograms, and regression analysis.
Conclusions:
- ANNs-LMB provides an effective and precise numerical approach for the nonlinear dengue fever SIR model.
- The method shows strong potential for epidemiological forecasting and public health interventions.
- Validation metrics confirm the robustness and competence of the ANNs-LMB technique.
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