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Updated: Oct 3, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
How do freshwater microalgae and cyanobacteria respond to antibiotics?
Ve Van Le1,2, Quynh-Giao Tran1, So-Ra Ko1
1Cell Factory Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea.
Antibiotic pollution harms aquatic life, impacting primary producers like microalgae and cyanobacteria. This review explores their biological responses and adaptive mechanisms to antibiotic exposure, highlighting potential for bioremediation.
Area of Science:
- Environmental Science
- Ecotoxicology
- Microbiology
Background:
- Antibiotic residues from anthropogenic sources contaminate freshwater ecosystems.
- These contaminants create reservoirs for antibiotic resistance development.
- Microalgae and cyanobacteria, as primary producers, are vital to monitor for antibiotic impacts.
Purpose of the Study:
- To review the effects of antibiotics on microalgae and cyanobacteria.
- To discuss adaptive mechanisms of these organisms to antibiotic exposure.
- To highlight factors influencing antibiotic removal by microalgae for technological applications.
Main Methods:
- Literature review of studies on antibiotic effects on freshwater microalgae and cyanobacteria.
- Analysis of biological processes affected: photosynthesis, oxidative stress, macromolecule metabolism.
- Examination of adaptive strategies: biodegradation, bioadsorption, bioaccumulation.
Main Results:
- Antibiotics disrupt photosynthesis, induce oxidative stress, and alter macromolecule metabolism in microalgae and cyanobacteria.
- Organisms exhibit adaptive mechanisms including biodegradation, bioadsorption, and bioaccumulation.
- Factors influencing these removal pathways are identified.
Conclusions:
- Understanding antibiotic impacts and adaptive mechanisms is crucial for aquatic ecosystem health.
- Microalgae-based technologies show promise for antibiotic removal from contaminated waters.
- Further research is needed to optimize these applications.
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