Nfkbid-mediated humoral immunity during secondary toxoplasmosis
Imtiaz A Khan1, Magali Moretto1
1Department of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington, DC 20037, USA.
Trends in Parasitology
|February 22, 2022
Abstract:
Vaccine-mediated immunity to parasites has not been achieved. Immune C57BL/6 mice are susceptible to secondary Toxoplasma gondii infection. Using a forward genetics approach, Souza et al. identify Nfkbid as an important factor for the regulation of B cell immunity during secondary Toxoplasma infection and protection against rechallenge.
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