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Correlation between bispectral index and patient state index in children under sevoflurane anesthesia

Doyeon Kim1, Jaeyoun Kim1, Inho Kim1

  • 1Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Paediatric Anaesthesia
|February 22, 2022
PubMed

Insights

This study found a fair correlation between Bispectral Index (BIS) and Patient State Index (PSI) in children undergoing sevoflurane anesthesia. However, neither BIS nor PSI is reliable for monitoring anesthesia depth in pediatric patients.

Area of Science:

  • Anesthesiology
  • Pediatric Anesthesia
  • Neurophysiology

Background:

  • Managing anesthesia depth in children is crucial to prevent adverse physical and emotional outcomes.
  • Unanticipated arousal or hemodynamic instability can negatively impact pediatric patients.

Purpose of the Study:

  • To compare the Bispectral Index (BIS) and Patient State Index (PSI) in children during sevoflurane anesthesia.
  • To evaluate the reliability of PSI as a monitor for anesthesia depth in pediatric patients aged 6 months to 12 years.

Main Methods:

  • Prospective observational study of children (6 months-12 years) undergoing elective surgery.
  • Monitoring BIS and PSI at varying sevoflurane concentrations (1, 1.5, 2 MAC).
  • Analyzing correlations between BIS and PSI across different age groups and sevoflurane doses.

Main Results:

  • A fair correlation (r=0.430) was observed between BIS and PSI overall.
  • Fair correlations were noted at different sevoflurane concentrations and in specific age groups (6 months-2 years, 8-12 years).
  • No significant correlation was found in the 2-7 years age group.

Conclusions:

  • A fair correlation exists between BIS and PSI in pediatric patients under sevoflurane anesthesia.
  • Neither BIS nor PSI is a reliable indicator for monitoring anesthesia depth in pediatric patients receiving sevoflurane.
  • Further research may be needed to identify reliable depth of anesthesia monitors for children.
Abstract

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