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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
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Related Experiment Video

Updated: Oct 2, 2025

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Recent progress in three-dimensionally-printed dosage forms from a pharmacist perspective.

Ahmad Fahmi Bin Anwar-Fadzil1, Yunong Yuan1, Lingxin Wang1

  • 1School of Pharmacy, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.

The Journal of Pharmacy and Pharmacology
|February 22, 2022
PubMed
Summary
This summary is machine-generated.

Additive manufacturing (AM), or 3D printing (3DP), enables personalized pharmaceutical dosage forms. This technology allows for intricate designs, tailored dosing, and controlled drug release, revolutionizing pharmacy practice.

Keywords:
3D printingdosage formimplantoral drug deliverypharmacisttransdermal

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Area of Science:

  • Pharmaceutical Sciences
  • Materials Science
  • Manufacturing Engineering

Background:

  • Additive manufacturing (AM), widely known as 3D printing (3DP), is transforming pharmaceutical applications.
  • 3DP offers novel approaches to drug formulation and delivery systems.

Purpose of the Study:

  • To review recent advancements in 3D-printed pharmaceutical dosage forms from a pharmacist's viewpoint.
  • To explore the potential of 3DP in personalized medicine and compounding pharmacy.

Main Methods:

  • Literature search using keywords: additive manufacturing, 3D printing, drug delivery.
  • Databases searched: PubMed, EMBASE, Web of Science.
  • Focus on articles published in 2020.

Main Results:

  • 3DP applications span various dosage forms: oral, transdermal, rectal, vaginal, implants, and bone scaffolding.
  • Key areas discussed include patient-specific dosing, customizable administration, multidrug formulations, and controlled release profiles.
  • AM is poised to become integral to compounding pharmacies for polypills and personalized medications.

Conclusions:

  • 3D printing facilitates the creation of dosage forms with complex structures, precise dosing, and combined therapies.
  • The technology's ability to achieve tailored drug release and personalization is set to revolutionize pharmacy practice.