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Structure and Bonding
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Well-defined cyclic silanol derivatives.

Yujia Liu1, Thanawat Chaiprasert2, Armelle Ouali3

  • 1Department of Chemistry and Chemical Biology, Graduate School of Science and Technology, Gunma University, 1-5-1 Tenjin-cho, Kiryu 376-8515, Japan. unno@gunma-u.ac.jp.

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|February 22, 2022
PubMed
Summary
This summary is machine-generated.

Cyclic silanol derivatives (CSDs) are key precursors for hybrid materials. This review details synthetic routes and functionalization of CSDs, particularly cyclotetrasiloxanes, for future applications.

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Area of Science:

  • Organosilicon Chemistry
  • Materials Science
  • Synthetic Chemistry

Background:

  • Cyclic silanol derivatives (CSDs) feature siloxane rings composed of silicon and oxygen atoms.
  • CSDs serve as essential precursors for synthesizing well-defined building blocks for hybrid materials, including cyclic, cage, and ladder-type siloxane structures (SQs).
  • The historical development of CSD synthesis dates back to the first reported example in 1965.

Purpose of the Study:

  • To provide a comprehensive overview of synthetic routes for stereoregular cyclic silanol derivatives (CSDs) with varying siloxane ring sizes.
  • To summarize the state-of-the-art in CSD synthesis, including reaction conditions and 29Si NMR chemical shifts.
  • To explore the functionalization of CSDs, particularly all-cis-cyclotetrasiloxanes (T4), and discuss their potential applications.

Main Methods:

  • Review of established synthetic methodologies for cyclic silanol derivatives (CSDs).
  • Compilation and presentation of typical reaction conditions and 29Si NMR data for various CSDs.
  • Detailed examination of the synthesis and functionalization strategies for all-cis-cyclotetrasiloxanes (T4).

Main Results:

  • A systematic presentation of synthetic routes to numerous stereoregular CSDs with diverse siloxane ring sizes.
  • Tabulated data on reaction conditions and 29Si NMR chemical shifts for characterized CSDs.
  • Methodical exposition of the synthesis and organic functionalization of all-cis-cyclotetrasiloxanes (T4).

Conclusions:

  • Cyclic silanol derivatives (CSDs) are versatile precursors for advanced hybrid materials.
  • The review consolidates knowledge on CSD synthesis and functionalization, highlighting all-cis-cyclotetrasiloxanes (T4).
  • CSDs hold significant potential for future research and diverse applications in materials science.