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Published on: October 25, 2015
Fetomaternal hemorrhage assessment in Rh-negative patients undergoing dilation and evacuation between 20 and 24
Anne N Flynn1, Elizabeth Hoffman2, Christina Murphy1
1Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia PA, United States.
Objective:
To estimate the rate of requiring more than one 300-mcg Rh D immune globulin dose for fetomaternal hemorrhage (FMH) at the time of second-trimester dilation and evacuation (D + E).
Study Design:
We performed a retrospective cohort analysis of patients at greater than 20 weeks' gestation who underwent D + E, had Rh D-negative blood type, and received FMH quantification testing.
Results:
Of 25 eligible patients, 24 had negative quantification of FMH; one had positive quantification that did not meet the clinical threshold for additional dosing.
Conclusions:
The absolute risk of requiring additional Rh D immune globulin after D+E for pregnancies greater than 20 weeks' gestation was 0%.
