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Associations between toxic elements and blood pressure parameters in adolescents
Siddika Songül Yalçin1, İzzet Erdal1, Berna Oğuz2
1Division of Social Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Summary
Exposure to toxic elements like mercury and cadmium is linked to higher blood pressure (BP) in adolescents. This study found associations between elevated urinary mercury and cadmium levels and increased BP, particularly daytime readings.
Area of Science:
- Environmental Health
- Cardiovascular Health
- Pediatric Health
Background:
- Toxic element exposure and hypertension are significant global health concerns.
- Adolescent health is particularly vulnerable to environmental toxicant impacts.
- Understanding the link between toxic elements and blood pressure in youth is crucial.
Purpose of the Study:
- To investigate the association between urinary toxic elements and blood pressure (BP) in adolescents.
- To examine the relationship between toxic elements and diurnal BP variations.
- To identify specific toxic elements linked to hypertension in this age group.
Main Methods:
- Cross-sectional study including 48 hypertensive and 38 normotensive adolescents.
- Measured anthropometrics, urinary toxic elements (ICP-MS), cIMT, and office/ambulatory BP.
- Used logistic regression to analyze associations between elements (grouped by tertiles) and BP parameters.
Main Results:
- Detectable levels of cadmium, mercury, lead, and arsenic were common in adolescent urine.
- Elevated daytime systolic and/or diastolic BP correlated with urinary cadmium and mercury.
- Higher urinary mercury and cadmium levels were significantly associated with elevated 24-hour BP and mean arterial pressure.
Conclusions:
- Complex relationships exist between toxic element exposure and BP in adolescents.
- Urinary mercury and cadmium are associated with hypertension and elevated 24-hour BP in this population.
- Further research is needed to elucidate the long-term implications of these associations.
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