Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Unrenewable Cells

Unrenewable Cells

In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Partial hearing recovery after cochlear nerve surface transplantation of hair follicle-derived neural crest stem cells in neural hearing loss rat.

Animal models and experimental medicine·2026

Same author

Efficacy predictions for omalizumab treatment based on basophil CD203c expression in patients with allergic rhinitis by basophil activation test -- a real-life, pilot study.

The World Allergy Organization journal·2026

Same author

Isolation and Culture of Primary Marginal Cells of the Stria Vascularis from Neonatal Mice.

Journal of visualized experiments : JoVE·2026

Same author

Efficacy and safety of olopatadine-mometasone combination nasal spray for the treatment of seasonal allergic rhinitis.

The World Allergy Organization journal·2026

Same author

A novel non-sense variant in <i>GSDME</i> causing exon skipping associated with DFNA5 in a large Chinese family.

Frontiers in neurology·2026

Same author

Multi-omics and experimental validation identify methylation-related genes and METTL16 as key regulators in diabetic foot ulcer pathogenesis.

Scientific reports·2025

Search research articles

Related Experiment Video

Updated: Oct 2, 2025

A Protocol for Decellularizing Mouse Cochleae for Inner Ear Tissue Engineering

A Protocol for Decellularizing Mouse Cochleae for Inner Ear Tissue Engineering

Published on: January 1, 2018

[Advances in stem cell inner ear transplantation].

Rongkai Hua, Qingquan Hua

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery

|February 23, 2022

Summary

Stem cell inner ear transplantation shows promise for treating sensorineural hearing loss. Key considerations include stem cell source, delivery method, and managing immune rejection for successful outcomes.

Keywords:

hearing loss, sensorineural stem cells transplantation

More Related Videos

Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice

Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice

Published on: May 25, 2018

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse

Published on: March 2, 2018

Related Experiment Videos

Last Updated: Oct 2, 2025

A Protocol for Decellularizing Mouse Cochleae for Inner Ear Tissue Engineering

A Protocol for Decellularizing Mouse Cochleae for Inner Ear Tissue Engineering

Published on: January 1, 2018

Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice

Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice

Published on: May 25, 2018

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse

Published on: March 2, 2018

Area of Science:

Otology
Regenerative Medicine
Stem Cell Therapy

Background:

Sensorineural hearing loss is a prevalent otologic condition.
Stem cell therapy offers a potential regenerative approach for hearing loss.
Inner ear stem cell transplantation is an emerging treatment modality.

Purpose of the Study:

To review critical aspects of stem cell inner ear transplantation.
To discuss the influence of stem cell source and transplantation route.
To highlight the importance of addressing immune rejection post-transplantation.

Main Methods:

Literature review of current research on stem cell inner ear transplantation.
Analysis of studies focusing on stem cell sources.
Examination of different transplantation routes and immune modulation strategies.

Main Results:

Stem cell source selection impacts therapeutic efficacy.
Transplantation route influences cell survival and integration.
Immune rejection remains a significant challenge in post-transplantation care.

Conclusions:

Optimizing stem cell source and transplantation technique is vital.
Effective management of immune rejection is crucial for successful outcomes.
Further research is needed to refine stem cell inner ear transplantation protocols.