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Updated: Oct 2, 2025

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells
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Published on: May 30, 2025

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CRISPR in cancer biology and therapy

Alyna Katti1,2, Bianca J Diaz1,2, Christina M Caragine3,4

  • 1Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.

Nature Reviews. Cancer
|February 23, 2022
PubMed

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Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
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