Changes in origin of acute chest pain in a sub-Saharan African setting

Mark Tettey1,2, Frank Edwin2,3, Alfred Doku1,2

  • 1School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.

Tropical Doctor
|February 23, 2022
PubMed

Insights

The epidemiology of acute chest pain in Ghana is changing, highlighting an urgent need for increased physician awareness and improved clinical practices. This study investigated patients with acute chest pain at major Accra hospitals.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Acute chest pain is a common presentation in emergency departments globally.
  • Understanding the evolving epidemiology of acute chest pain is crucial for public health strategies.
  • Ghana, like many low- and middle-income countries, faces unique challenges in managing cardiovascular diseases.

Purpose of the Study:

  • To investigate the shifting epidemiology of acute chest pain in Ghana.
  • To assess the current landscape of acute chest pain presentations in tertiary care settings.
  • To underscore the need for enhanced physician awareness and best practices in managing acute chest pain.

Main Methods:

  • Retrospective analysis of patients presenting with acute chest pain.
  • Data collection from two leading tertiary care centers in Accra, Ghana.
  • Epidemiological investigation of patient demographics, risk factors, and clinical characteristics.

Main Results:

  • The study identified a changing pattern in the causes and characteristics of acute chest pain presentations.
  • Key demographic and clinical factors associated with acute chest pain were elucidated.
  • Significant variations in presentation and management were observed.

Conclusions:

  • The epidemiology of acute chest pain in Ghana is dynamic and requires continuous monitoring.
  • There is a pressing need to enhance physician education and adherence to best practices for acute chest pain management.
  • Interventions aimed at improving early diagnosis and treatment are essential for better patient outcomes.

Related Concept Videos

Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
42
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
36
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
67
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
103
Angina I: Introduction01:30

Angina I: Introduction

Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
55
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
51