Allergic contact cheilitis caused by propolis: case report.

Area of Science:

• Dermatology
• Allergology
• Natural Products Research

Background:

• Propolis, a resin collected by bees from plants, is increasingly used for its perceived health benefits.
• Allergic contact cheilitis is a persistent inflammation of the lips, often triggered by external allergens.
• The use of natural products for immune support has surged, particularly during the COVID-19 pandemic.

Observation:

• A 21-year-old female presented with a 5-year history of pruritic perioral eczema, which recently spread to her neck.
• Patch testing revealed a strong positive reaction to propolis and a weaker reaction to perfume mix I.
• The patient reported a decade-long history of ingesting propolis drops for immune enhancement, with increased dosage during the pandemic.

Findings:

• The patient was diagnosed with allergic contact cheilitis attributed to propolis.
• Propolis was identified as the primary sensitizer, with perfume mix I as a secondary finding.
• The patient's increased propolis consumption correlated with the exacerbation of her cheilitis symptoms.

Implications:

• Propolis allergy should be considered in the differential diagnosis of chronic or refractory cheilitis.
• The widespread popularity of natural products like propolis may lead to an increase in contact allergies.
• Healthcare providers should counsel patients on the potential allergens present in natural health products and supplements.