Related Experiment Video

Updated: Oct 2, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

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Retraction

    Journal of Cellular Physiology
    |February 23, 2022
    PubMed

    Insights

    This study on resistin's role in pancreatic cancer has been retracted due to unintentional research errors. The findings regarding resistin, CAP1, and TLR4 in cancer progression and chemoresistance are now considered invalid.

    Area of Science:

    • Oncology
    • Molecular Biology
    • Cell Biology

    Context:

    • Pancreatic cancer is a leading cause of cancer-related mortality.
    • Understanding the molecular mechanisms driving pancreatic cancer progression and chemoresistance is crucial for developing effective therapies.

    Purpose:

    • To investigate the role of resistin and its receptors, CAP1 and TLR4, in pancreatic cancer progression and chemoresistance.

    Summary:

    • The article "Resistin effects on pancreatic cancer progression and chemoresistance are mediated through its receptors CAP1 and TLR4" has been retracted.
    • The retraction was requested by the authors due to unintentional errors during the research process.
    • Consequently, the experimental results cannot be verified, and the conclusions are deemed invalid.

    Impact:

    • The retraction invalidates previous findings on resistin's mechanism in pancreatic cancer.
    • This necessitates a re-evaluation of resistin's potential as a therapeutic target or biomarker in pancreatic cancer.

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