Related Experiment Video

Updated: Oct 2, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.4K

Epidemiological and clinical risk factors related to severe COVID-19 in Iran: a multi-center study

Seyed Mohammad Hashemi-Shahri1, Seyed Mohammad Nasiraldin Tabatabaei2, Alireza Ansari-Moghaddam3

  • 1Research Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

BMC Infectious Diseases
|February 24, 2022
PubMed

Insights

Older age, substance abuse, and underlying diseases significantly increase the risk of severe COVID-19. Understanding these factors is crucial for managing the pandemic, especially in resource-limited regions.

Area of Science:

  • Epidemiology
  • Clinical Medicine
  • Public Health

Background:

  • COVID-19 significantly impacted Iran early in the pandemic.
  • Identifying COVID-19 severity factors aids disease management.
  • This study focused on a less privileged region in Iran.

Purpose of the Study:

  • To investigate epidemiological and clinical features of COVID-19.
  • To identify factors associated with COVID-19 severity.
  • To inform disease management strategies in underserved areas.

Main Methods:

  • Multi-center study of patients admitted to Zahedan University of Medical Sciences hospitals (February-April 2020).
  • Extracted demographic, epidemiological, and clinical data from medical records.
  • Utilized bivariate and multivariate logistic regression to identify risk factors for severity.

Main Results:

  • Out of 413 patients, 35.10% presented with severe COVID-19.
  • Older age was associated with increased odds of severe disease (OR 2.27).
  • Substance abuse (OR 2.49) and multiple underlying diseases (OR 1.52-2.60) were significant risk factors for severity.

Conclusions:

  • COVID-19 severity is notably higher in older individuals, those with substance abuse history, and patients with comorbidities.
  • These findings are vital for optimizing clinical management of COVID-19.
  • Understanding risk factors is particularly important for resource-constrained settings.
Abstract

Keywords:
COVID-19PatientsRisk factorsSeverity

More Related Videos

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-1906:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

2.5K
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.4K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.6K
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
4.6K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
662
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
753
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
35
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.6K