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Peripherical Electrical Stimulation for Parkinsonian Tremor: A Systematic Review
Lin Meng1, Mengyue Jin1, Xiaodong Zhu2
1Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Frontiers in Aging Neuroscience
|February 24, 2022
Summary
Electrical stimulation effectively reduces Parkinsonian tremor, offering a non-invasive alternative. Functional electrical stimulation (FES) shows the most promise, though mechanisms for sensory and transcutaneous methods require further research.
Area of Science:
- Neurology
- Biomedical Engineering
Background:
- Parkinsonian tremor is a common motor disorder in Parkinson's disease (PD).
- Electrical stimulation presents a non-invasive alternative to oral medications and surgery for tremor reduction.
- A systematic review of peripheral electrical stimulation for PD tremor is lacking.
Approach:
- Reviewed 20 studies (2010-2021) on electrical stimulation for PD tremor suppression.
- Categorized methods into functional electrical stimulation (FES), sensory electrical stimulation (SES), and transcutaneous electrical nerve stimulation (TENS).
- Analyzed stimulation protocols, methodologies, and clinical outcomes.
Key Points:
- Electrical stimulation is an efficient intervention for tremor suppression in PD.
- FES demonstrated the best tremor attenuation, contingent on control strategy and detection accuracy.
- Outcomes varied based on stimulation approach, electrode placement, and parameters.
Conclusions:
- Electrical stimulation is a viable option for PD tremor management.
- Further research is needed to elucidate the mechanisms of SES and TENS for tremor suppression.
- Current methods may not be universally effective, necessitating exploration of underlying mechanisms.
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