Related Experiment Video

Updated: Oct 2, 2025

Quantification of Atherosclerosis in Mice
06:59

Quantification of Atherosclerosis in Mice

Published on: June 12, 2019

38.6K

Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H

Kevin P Kotredes1, Adrian Oblak2, Ravi S Pandey1

  • 1The Jackson Laboratory, Bar Harbor, ME, United States.

Frontiers in Aging Neuroscience
|February 24, 2022
PubMed

Abstract:

[This corrects the article DOI: 10.3389/fnagi.2021.735524.].

Keywords:
ApoE4MODEL-ADTREM2late-onset ADmouse model

More Related Videos

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.4K
Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
08:01

Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits

Published on: March 16, 2016

43.1K

Related Experiment Videos

Last Updated: Oct 2, 2025

Quantification of Atherosclerosis in Mice
06:59

Quantification of Atherosclerosis in Mice

Published on: June 12, 2019

38.6K
A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.4K
Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
08:01

Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits

Published on: March 16, 2016

43.1K

Related Concept Videos

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

5.8K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.8K

Articles linked to this work by shared authors, journal, and citation graph.

Molecular Glue Degraders Enhance CAPRIN1-Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Inhibition of Moesin and CD44 in stem cell-derived neurons affects the pathological genetic signature associated with Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

A collaborative framework for uncovering molecular and cellular drivers of VCID: Foundations for future interventions in dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

The past, the present, and the future of preclinical mouse models for Alzheimer's disease and related dementias.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

A complete genome for the common marmoset.

Cell·2026

Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Global research trends and hotspots in blood-based biomarkers for Alzheimer's disease: a bibliometric analysis.

Frontiers in aging neuroscience·2026

Age-related differences in behavioral and brain predictors of parkinsonism in autistic adults.

Frontiers in aging neuroscience·2026

Persistent Alzheimer-related molecular dysregulation after cerebral ischemia: a hierarchical-circular hypothesis of impaired allostatic recovery.

Frontiers in aging neuroscience·2026

Multimodal neuroimaging and electrophysiological signatures in amnestic mild cognitive impairment with different amyloid-β deposition status: correlations with cognitive function and diagnostic value.

Frontiers in aging neuroscience·2026

Muscle quality index combined with plasma metabolomics: enhancing risk stratification for post-stroke dementia.

Frontiers in aging neuroscience·2026

Clemastine alleviates Parkinson's disease pathology by activating the AMPK/mTOR pathway and enhancing autophagic flux.

Frontiers in aging neuroscience·2026

Atractylenolide III attenuates age-related vertebral bone loss by suppressing macrophage inflammation and osteoclastogenesis.

Bone reports·2026

Endovascular retrieval of bone cement entrapped in an inferior vena cava filter after percutaneous vertebroplasty: a case report.

Frontiers in surgery·2026

Betaine restores OPA1-mediated mitochondrial fusion in alveolar epithelial type 2 cells and ameliorates hyperoxic lung injury in newborn mice.

Frontiers in cell and developmental biology·2026

Efficacy of Defibrinogenation Therapy for Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis.

Laryngoscope investigative otolaryngology·2026

A TRIM15-CDX2 loop drives bile acid-induced gastric intestinal metaplasia.

Molecular medicine (Cambridge, Mass.)·2026

[Mechanism of Xiaoyao Kangai Jieyu Formula in improving hippocampal neurovascular unit damage in breast cancer-related depression via HMGB1/TLR4 signaling pathway].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us