Non-inferiority trials

Priya Ranganathan1, C S Pramesh2, Rakesh Aggarwal3

  • 1Department of Anaesthesiology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

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Testing a Claim about Population Proportion01:24

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A complete procedure for testing a claim about a population proportion is provided here.
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Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
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