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Recent Advances in Vertical Alveolar Bone Augmentation Using Additive Manufacturing Technologies.

Cedryck Vaquette1, Joshua Mitchell1, Sašo Ivanovski1

  • 1School of Dentistry, Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3), The University of Queensland, Herston, QLD, Australia.

Frontiers in Bioengineering and Biotechnology
|February 24, 2022
PubMed
Summary

Additive manufacturing, or 3D printing, offers advanced scaffolds for vertical bone augmentation. These 3D printed materials overcome limitations of traditional methods, improving bone regeneration and clinical outcomes.

Keywords:
3D-printingBMP-2bioceramicbone regenerationextraskeletal bonepolycaprolactone

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Area of Science:

  • Biomaterials Engineering
  • Regenerative Medicine
  • Oral and Maxillofacial Surgery

Background:

  • Vertical bone augmentation is crucial for restoring bone height in cases of moderate to severe oral atrophy.
  • Current techniques like autologous bone blocks and Guided Bone Regeneration (GBR) have significant limitations including morbidity and high failure rates.

Purpose of the Study:

  • To critically review advancements in additive manufacturing (3D printing) for vertical bone augmentation.
  • To assess the application of 3D printed scaffolds, membranes, and meshes in Guided Bone Regeneration (GBR).

Main Methods:

  • Review of recent literature on additive manufacturing technologies for bone regeneration scaffolds.
  • Analysis of 3D printing applications in vertical bone augmentation and GBR, including in vivo studies.

Main Results:

  • Additive manufacturing enables the creation of highly porous, interconnected 3D scaffolds.
  • These scaffolds promote vascularization and osteogenesis, offering improved handling and space-maintaining properties.
  • 3D printed constructs show promise in overcoming limitations of conventional augmentation techniques.

Conclusions:

  • Additive manufacturing presents a promising alternative for fabricating devices for vertical bone augmentation and GBR.
  • 3D printed scaffolds offer enhanced potential for bone regeneration compared to existing methods.