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The shifting care and outcomes for patients with endangered limbs - Critical limb ischemia (SCOPE-CLI) registry

Lindsey E Scierka1, Carlos Mena-Hurtado1, Mehdi H Shishehbor2

  • 1Yale University, Department of Internal Medicine, Vascular Medicine Outcomes Program (VAMOS), New Haven, CT, United States.

International Journal of Cardiology. Heart & Vasculature
|February 24, 2022
PubMed

Insights

The SCOPE-CLI study co-designs care for critical limb ischemia (CLI) patients, capturing their experiences and preferences to improve outcomes. This research aims to address gaps in CLI care quality.

Area of Science:

  • Vascular Medicine
  • Patient-Centered Outcomes Research
  • Peripheral Artery Disease

Background:

  • Critical limb ischemia (CLI) is a severe form of peripheral artery disease with high amputation and mortality rates.
  • Patient perspectives on care processes, preferences, and outcomes in CLI are poorly understood.
  • The SCOPE-CLI study was co-designed with patients to address these knowledge gaps.

Purpose of the Study:

  • To holistically document patient characteristics, treatment preferences, and patterns of care for individuals with CLI.
  • To capture patient-centered outcomes from the perspective of those affected by CLI.
  • To identify and address disparities in the quality of care and outcomes for CLI patients.

Main Methods:

  • An 11-center prospective observational registry enrolling 816 patients with CLI in the US and Australia.
  • Patients are interviewed and followed for 12 months, with vital status tracked for 5 years.
  • Data collection includes psychosocial factors, health status, hospitalizations, interventions, and patient-reported outcomes.

Main Results:

  • Pilot data from 3 centers enrolled 70 patients.
  • The initial cohort had a mean age of 68.4 years, with 31.4% females and 20.0% African Americans.
  • Enrollment and data collection are ongoing.

Conclusions:

  • The SCOPE-CLI study, co-designed with patients, offers a unique approach to understanding the CLI population.
  • Findings will provide crucial insights into care experiences, treatment preferences, and health status outcomes.
  • This research is vital for improving the quality of care and outcomes for this vulnerable patient group.
Abstract

Keywords:
Critical Limb IschemiaHealth DisparitiesPatient-Reported OutcomesPeripheral Artery DiseaseRegistriesStudy Design

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