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Multisystem Inflammatory Syndrome in Children Unmasking Brugada Type 1 Pattern
Carla G Corti1, Alessandro Seganti2, Antonio Sanzo2
1Pediatric Cardiology, Department of Pediatrics, Children's Hospital Vittore Buzzi, Milan, Italy.
JACC. Case Reports
|February 24, 2022
Summary
Multisystem inflammatory syndrome in children can trigger cardiac issues like atrial fibrillation and Brugada syndrome in adolescents. Early detection and diagnosis are crucial for managing these serious pediatric conditions.
Area of Science:
- Pediatric Cardiology
- Electrophysiology
- Infectious Diseases
Background:
- Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition that can affect multiple organs, including the heart.
- Cardiac complications, such as arrhythmias, can occur during the acute and subacute phases of MIS-C.
Observation:
- A 14-year-old boy with MIS-C presented with atrial fibrillation during the acute phase.
- He subsequently developed a transient Brugada type 1 electrocardiogram pattern in the subacute phase.
Findings:
- An ajmaline provocative test eight months later confirmed a diagnosis of Brugada syndrome.
- This case highlights a potential association between MIS-C and the development of Brugada syndrome.
Implications:
- Clinicians should consider cardiac monitoring for arrhythmias in children with MIS-C.
- Further research is needed to understand the long-term cardiac implications of MIS-C and its potential link to channelopathies like Brugada syndrome.
Keywords:
BP, Brugada phenocopyBrS, Brugada syndromeBrugada phenocopyBrugada syndromeECG, electrocardiographicMIS-C, multisystem inflammatory syndrome in childrenMPL, modified precordial leadSARS-CoV-2, severe acute respiratory syndrome-coronavirus-2autonomic system dysregulationcytokine stormmultisystem inflammatory syndrome in childrenMore Related Videos
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