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Detection and Quantification of Tunneling Nanotubes Using 3D Volume View Images
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Unearthing the Tunnel.

Yaser Nemshah1,2, Anjali Sharma1, Nadira Hamid1

  • 1Columbia Heart and Valve Center, NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, New York, USA.

JACC. Case Reports
|February 24, 2022
PubMed
Summary
This summary is machine-generated.

A paravalvular leak occurred around a bioprosthetic mitral valve. Advanced imaging and new technology identified the leak

Keywords:
2D, 2-dimensional3D3D, 3-dimensionalAVP II, Amplatzer Vascular Plug IICT, computed tomographyPVL, paravalvular leakTEE, transesophageal echocardiogramchannelechocardiographymitral regurgitationparavalvular leakpercutaneous closure

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Paravalvular leaks (PVLs) are potential complications following prosthetic valve replacement.
  • Bioprosthetic mitral valves can be susceptible to paravalvular complications.
  • Accurate characterization of PVLs is crucial for effective management.

Observation:

  • A unique case of a paravalvular leak was identified.
  • The leak originated from a periannular channel surrounding a bioprosthetic mitral valve.
  • The complex trajectory of the regurgitant jet was visualized.

Findings:

  • Multimodality imaging played a critical role in diagnosing the PVL.
  • Novel imaging technologies were employed to delineate the leak's origin and path.
  • The detailed anatomical understanding facilitated successful procedural intervention.

Implications:

  • This case highlights the importance of advanced imaging in managing complex paravalvular leaks.
  • Successful intervention for PVLs can be achieved with precise anatomical localization.
  • Findings may inform future strategies for diagnosing and treating prosthetic valve complications.