Silent Myocardial Infarction and Acute Multiorgan Failure in a COVID-19 Patient: A Case Report

Nischit Baral1, Andrea Montalbano2, Ashiya Khan1

  • 1Department of Internal Medicine, Mclaren Flint/Michigan State University College of Human Medicine, United States of America.

Insights

Silent myocardial infarction (SMI) is more common in older adults. This case report highlights SMI in a COVID-19 patient, emphasizing the need for cardiac evaluation in all COVID-19 cases, especially the elderly.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Geriatrics

Background:

  • Silent myocardial infarction (SMI) is increasingly recognized in elderly individuals with cardiovascular risk factors.
  • The prevalence of SMI in patients with COVID-19 remains largely unknown.
  • COVID-19 is associated with cardiovascular complications, but silent presentations are not well-documented.

Observation:

  • A 77-year-old male with COVID-19 pneumonia presented with diabetic ketoacidosis and multiorgan failure.
  • The patient experienced a silent ST-segment elevation myocardial infarction (STEMI) without typical anginal symptoms.
  • This represents the first reported case of SMI in a COVID-19 patient.

Findings:

  • Cardiac catheterization revealed ostial right coronary artery stenosis.
  • A drug-eluting stent was successfully placed following a specialized safety protocol.
  • The patient was discharged in stable condition to an extended-care facility.

Implications:

  • COVID-19 patients, particularly the elderly, require cardiac evaluation for acute myocardial infarction, even in the absence of symptoms.
  • Prompt diagnosis and intervention for myocardial infarction in COVID-19 patients, using appropriate safety measures, can be life-saving.
  • This case underscores the importance of considering silent myocardial infarction in the differential diagnosis of COVID-19 presentations.

Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...