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Mucormycosis: An unanticipated progeny of COVID-19

Gentle Sunder Shrestha1, Sabin Bhandari1, Ritesh Lamsal1

  • 1Department of Anaesthesiology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association
|February 24, 2022
PubMed

Insights

The COVID-19 pandemic increased mucormycosis infections in Nepal. Early prevention strategies are crucial for low-income countries to combat this fungal infection in patients with COVID-19.

Area of Science:

  • Infectious Diseases
  • Mycology
  • Public Health

Background:

  • The second wave of COVID-19 overwhelmed healthcare systems in Nepal and surrounding regions.
  • An increase in mucormycosis cases co-occurring with COVID-19 has been observed in Nepal and India.
  • Mucormycosis presents a significant challenge, particularly in resource-limited settings.

Purpose of the Study:

  • To describe the clinical presentation, diagnosis, and risk factors of mucormycosis in COVID-19 patients.
  • To investigate the reasons behind the increased susceptibility of COVID-19 patients to mucormycosis.
  • To emphasize the importance of prevention strategies for mucormycosis in low-income countries.

Main Methods:

  • Clinical case review and analysis of mucormycosis in COVID-19 patients.
  • Literature review on risk factors and pathogenesis of mucormycosis.
  • Exploration of epidemiological data from Nepal and India.

Main Results:

  • COVID-19 patients exhibit increased risk factors for developing mucormycosis.
  • The clinical presentation and diagnostic challenges of mucormycosis are detailed.
  • Specific risk factors contributing to mucormycosis in the context of COVID-19 are identified.

Conclusions:

  • Mucormycosis is a serious opportunistic infection in COVID-19 patients, requiring prompt diagnosis and management.
  • Understanding risk factors is key to preventing mucormycosis in vulnerable populations.
  • Simple preventive measures are vital for mitigating mucormycosis in resource-limited nations like Nepal.
Keywords:
COVID-19; mucormycosis; Nepal.

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