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Factors Affecting Drug Response: Overview

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...

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Optimizing Older Adults' Medication Use.

Mary C Zonsius¹, Klodiana Myftari, Michelle Newman

¹Mary C. Zonsius is an associate professor in the College of Nursing at Rush University Medical Center in Chicago, where Klodiana Myftari is a clinical pharmacy specialist in the Department of Ambulatory Care Management, Michelle Newman is a program manager in the Department of Social Work and Community Health, and Erin E. Emery-Tiburcio is an associate professor in the Department of Psychiatry and Behavioral Sciences. Myftari is also an assistant professor of pharmacy practice at Midwestern University College of Pharmacy in Downers Grove, IL. Contact author: Mary C. Zonsius, mary_c_zonsius@rush.edu . The authors have disclosed no potential conflicts of interest, financial or otherwise.

The American Journal of Nursing

|February 24, 2022

Summary

This summary is machine-generated.

This article introduces the 4Ms framework (What Matters, Medication, Mentation, Mobility) to support family caregivers in age-friendly health systems. It provides resources for nurses and caregivers to improve older adult care during hospital transitions.

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Area of Science:

Gerontology
Health Services Research
Caregiver Support

Background:

Family caregivers play a crucial role in the care of older adults.
Age-friendly health systems aim to optimize care for older populations.
The 4Ms framework provides a structured approach to assess and manage critical aspects of older adult care.

Purpose of the Study:

To present considerations for implementing the 4Ms framework in inpatient hospital settings.
To outline strategies for incorporating family caregivers into the 4Ms framework.
To provide resources for nurses and family caregivers to enhance the care of older adults.

Main Methods:

This article is part of a series focusing on supporting family caregivers within the 4Ms framework.
It discusses the application of the 4Ms framework in the hospital setting.
Accompanying resources include informational tear sheets and instructional videos.

Main Results:

Engaging healthcare teams, older adults, and family caregivers with the 4Ms framework improves care quality and patient satisfaction.
Implementation guidance is provided for the inpatient setting.
Resources are available to educate both nurses and family caregivers on the 4Ms framework.

Conclusions:

The 4Ms framework is an evidence-based approach to enhance care for older adults.
Integrating family caregivers into the 4Ms framework is essential for effective care delivery.
Resources are provided to facilitate the adoption and utilization of the 4Ms framework by healthcare professionals and caregivers.