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Additive Soft Matter Design by UV-Induced Polymer Hydrogel Inter-Crosslinking.

Talika A Neuendorf1, Niclas Weigel1, Michelle Vigogne1

  • 1Leibniz-Institut für Polymerforschung Dresden e. V., Hohe Straße 6, 01069 Dresden, Germany.

Gels (Basel, Switzerland)
|February 24, 2022
PubMed
Summary

This study introduces a novel UV-induced crosslinking method to connect different hydrogel building blocks, creating stable, multi-responsive 4D materials for advanced applications.

Keywords:
additive manufacturingassemblybuilding blockscrosslinkingdroplet microfluidicshydrogelphotopolymerization

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Soft Robotics

Background:

  • Stimuli-responsive hydrogels are key for 4D materials but often respond to single stimuli.
  • Multi-responsive materials require hierarchical assembly of diverse hydrogel building blocks.
  • Inter-connection stability is crucial for information transmission in complex 4D materials.

Purpose of the Study:

  • To investigate a UV-induced 2,3-dimethylmaleimide (DMMI) dimerization for inter-connecting hydrogel building blocks.
  • To create dual-crosslinked, multi-responsive hydrogel assemblies.
  • To assess the stability and processability of these assemblies.

Main Methods:

  • Utilized UV-induced 2,3-dimethylmaleimide (DMMI) dimerization.
  • Inter-connected acrylamide-based and N-isopropylacrylamide-based hydrogel cubes and spheres.
  • Evaluated stability through contraction-expansion cycles in various solvents.

Main Results:

  • Successfully created dual-crosslinked hydrogel assemblies with enhanced stability.
  • Demonstrated the method's applicability for both millimeter-sized cubes and microfluidically fabricated spheres.
  • Assemblies exhibited stability against contraction-expansion cycles in solution and different solvents.

Conclusions:

  • UV-induced DMMI dimerization is an effective strategy for creating stable, multi-responsive hydrogel assemblies.
  • This method enables the fabrication of complex 4D materials with potential in biomedicine and soft electronics.
  • The approach offers a pathway to advanced materials with programmed stimulus responses.