Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

8.0K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.0K
Ethical Issues01:27

Ethical Issues

1.3K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.3K
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

1.4K
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
1.4K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K
Current Trends in Nursing I01:28

Current Trends in Nursing I

1.7K
Current trends in nursing include:
1.7K
Cancer Survival Analysis01:21

Cancer Survival Analysis

473
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
473

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacodynamics of Camizestrant Treatment in Postmenopausal Women With Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Primary Breast Cancer: Results From the Randomized, Presurgical SERENA-3 Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Changing Practices in Axillary Surgery After Neoadjuvant Breast Cancer Therapy: Insights From the EUSOMA European Database.

Journal of surgical oncology·2025
Same author

Primary endocrine therapy versus surgery plus endocrine therapy for early-stage breast cancer in older women without frailty: a cost-effectiveness and value of implementation analysis.

Health economics review·2025
Same author

The Association Between Psychosocial Factors and Decision Making Regarding Primary Treatment in Older Women With Early-Stage Breast Cancer.

Psycho-oncology·2025
Same author

Updates and Future Directions for the Nottingham Research Programme on Primary Breast Cancer in Older Women.

Cancers·2025
Same author

Patient-Reported Outcomes in Geriatric Oncology-Balancing Quality of Life and Therapeutic Effectiveness Using Primary Breast Cancer as a Model.

Drugs & aging·2024

Related Experiment Video

Updated: Oct 2, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

723

Challenges in Geriatric Oncology-A Surgeon's Perspective.

Ruth Parks1, Kwok-Leung Cheung1,2

  • 1Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2RD, UK.

Current Oncology (Toronto, Ont.)
|February 24, 2022
PubMed
Summary

Older adults with cancer face unique challenges in treatment, including limited clinical trials and patient selection. Solutions involve prehabilitation, geriatric assessments, and collaborative care between surgeons and geriatricians.

Keywords:
cancerclinical trialsfrailtygeriatricianolder adultssurgical oncologist

More Related Videos

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

3.9K
Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.3K

Related Experiment Videos

Last Updated: Oct 2, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

723
Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

3.9K
Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.3K

Area of Science:

  • Geriatric Oncology
  • Surgical Oncology
  • Cancer Care in Older Adults

Background:

  • The global population is aging, leading to an increased incidence of cancer diagnoses in older adults.
  • Surgery is a primary treatment for solid tumors, but managing older cancer patients presents unique complexities.
  • Current approaches often lack tailored strategies for the specific needs of elderly cancer patients.

Purpose of the Study:

  • To review the challenges in managing older adults with cancer undergoing surgery.
  • To identify potential solutions and optimize treatment strategies for this demographic.
  • To highlight the need for integrated care models in geriatric cancer surgery.

Main Methods:

  • This is a narrative review synthesizing current literature on challenges and solutions.
  • It examines issues related to clinical trials, patient selection, and treatment optimization.
  • It discusses the role of prehabilitation, geriatric assessments, and enhanced recovery programs.

Main Results:

  • Key challenges include a deficit in high-level clinical trials for older adults and difficulties in selecting appropriate surgical candidates.
  • Individual patient vulnerabilities require identification and optimization, with prehabilitation showing promise.
  • Integrating geriatric assessments and fostering collaboration between surgical oncologists and geriatricians are crucial.

Conclusions:

  • Addressing the complexities of cancer care in older adults requires a multidisciplinary approach.
  • Tailored interventions like prehabilitation and enhanced recovery programs can improve outcomes.
  • A shift in clinician mindset towards shared care is essential for optimal patient management.