Related Experiment Video
Updated: Oct 2, 2025
08:48
Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
Published on: January 29, 2016
16.9K
An Individualized Exercise Intervention for People with Multiple Myeloma-Study Protocol of a Randomized
Jennifer L Nicol1,2, Carmel Woodrow3, Brent J Cunningham1
1School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane 4072, Australia.
Current Oncology (Toronto, Ont.)
|February 24, 2022
Summary
This study investigated if exercise improves health-related quality of life (HRQoL) for multiple myeloma (MM) patients. Results will guide exercise integration into standard MM care.
Area of Science:
- Oncology
- Exercise Science
- Quality of Life Research
Background:
- Multiple myeloma (MM) significantly impairs health-related quality of life (HRQoL), second only to lung cancer.
- Bone pain and lesions are common in MM, necessitating investigation into supportive therapies like exercise.
Purpose of the Study:
- To evaluate the efficacy of a structured exercise intervention in improving HRQoL for individuals with MM.
- To assess the impact of exercise on secondary outcomes including bone health, pain, fatigue, fitness, and body composition.
Main Methods:
- A randomized controlled trial involving 60 MM patients assigned to an exercise (EX) or waitlist control (WT) group.
- The EX group underwent a 12-week multimodal exercise program, followed by continued unsupervised training.
- HRQoL and secondary outcomes were measured at baseline and at 12, 24, and 52 weeks.
Main Results:
- Primary outcome: Patient-reported HRQoL.
- Secondary outcomes: Bone health, pain, fatigue, cardiorespiratory fitness, muscle strength, body composition, disease response, and blood biomarkers.
- Adverse events, attendance, adherence, and cost-effectiveness were also analyzed.
Conclusions:
- Findings will determine if exercise should be a standard component of care for MM patients.
- Exercise interventions may offer significant benefits for the HRQoL and overall health of this population.
