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Green algae, also referred to as chlorophytes, are different from red algae in having the chloroplasts containing chlorophylls a and b, which give them their distinct green hue. However, they lack phycobiliproteins, preventing them from developing the red or blue-green pigmentation seen in red algae. In terms of photosynthetic pigment composition, green algae closely resemble plants and share a close evolutionary relationship with them. Taxonomically Green algae belong to Phylum Chlorophyta in...
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Marine natural products.

Anthony R Carroll1,2, Brent R Copp3, Rohan A Davis2,4

  • 1School of Environment and Science, Griffith University, Gold Coast, Australia. A.Carroll@griffith.edu.au.

Natural Product Reports
|February 24, 2022
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Summary

This review details marine natural products (MNPs) discovered in 2020, highlighting 1407 new compounds from diverse marine organisms. It analyzes their biological activities and origins, offering a comprehensive overview of MNP research.

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Area of Science:

  • Marine Natural Products Chemistry
  • Marine Pharmacology
  • Marine Biodiversity

Background:

  • Marine natural products (MNPs) are a rich source of novel chemical structures.
  • Marine organisms, including microorganisms, algae, and invertebrates, produce a vast array of bioactive compounds.
  • The exploration of MNPs is crucial for drug discovery and understanding marine ecosystems.

Purpose of the Study:

  • To review and summarize the literature on marine natural products published in 2020.
  • To identify and document new compounds, their biological activities, and sources.
  • To provide an analysis of trends in MNP research over the last five years.

Main Methods:

  • Comprehensive literature search for publications in 2020 related to MNPs.
  • Cataloging of new compounds, including their chemical structures, biological activities, source organisms, and geographical origin.
  • Meta-analysis of bioactivity data for MNPs reported in the last five years.

Main Results:

  • A total of 757 citations were reviewed, focusing on 1407 new MNPs reported in 420 papers from 2020.
  • Compounds were isolated from a wide range of marine sources, including microorganisms, algae, sponges, and other invertebrates.
  • Included are details on biological activities, source organisms, country of origin, biosynthetic studies, and synthetic efforts.

Conclusions:

  • The year 2020 saw significant advancements in the discovery and characterization of marine natural products.
  • The diversity of marine sources continues to yield novel compounds with potential therapeutic applications.
  • This review provides a valuable resource for researchers in natural product chemistry and drug discovery.