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Perspectives in Sports Genomics.
Valentina Ginevičienė1, Algirdas Utkus1, Erinija Pranckevičienė1,2
1Institute of Biomedical Science, Faculty of Medicine, Vilnius University, 01513 Vilnius, Lithuania.
Biomedicines
|February 25, 2022
Summary
Sports genetics explores how genes influence athletic performance. Advances in genomics and multi-omics offer insights into training, injury prevention, and personalized sports medicine.
Area of Science:
- Exercise Science
- Sports Genetics
- Genomics
Background:
- Human athletic performance is a complex trait influenced by genetics and environment.
- Most exercise-related traits are polygenic, meaning multiple genes are involved.
- Sports genetics is an emerging field facing unique challenges.
Purpose of the Study:
- To review challenges and advances in sports genetics.
- To discuss the impact of genomics, epigenomics, and other 'omics' on athletic performance.
- To examine gene doping, injury risk prediction, and sudden death prevention in athletes.
Main Methods:
- Review of recent advances in sports science.
- Analysis of the influence of genome, epigenome, proteomics, and metabolomics.
- Examination of genetic knowledge application in sports medicine and performance.
Main Results:
- Identified challenges in the advancement of sports genetics.
- Highlighted the role of multi-omics in understanding athletic predispositions.
- Discussed potential applications in personalized coaching, nutrition, and injury prevention.
Conclusions:
- Future research in large athlete cohorts can identify new genetic variants.
- Genomic and multi-omics approaches can enhance performance analysis and sports medicine.
- Understanding genetic influences is crucial for optimizing athlete health and performance.
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