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OCT-Guided Surgery for Gliomas: Current Concept and Future Perspectives.

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Optical coherence tomography (OCT) offers real-time, high-resolution brain tumor imaging during surgery. This technology aids in precise tumor identification and resection, enhancing surgical outcomes.

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Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Oncology

Background:

  • Brain tumor surgery requires precise visualization for optimal outcomes.
  • Current imaging techniques have limitations in real-time, high-resolution tissue analysis.
  • Optical coherence tomography (OCT) emerges as a promising technology for intraoperative guidance.

Purpose of the Study:

  • To review the fundamentals of OCT imaging.
  • To explore OCT applications in neurosurgery for brain tumor resection.
  • To discuss the potential of OCT in improving surgical precision and safety.

Main Methods:

  • Review of existing literature on OCT technology and its neurosurgical applications.
  • Analysis of qualitative and quantitative OCT image interpretation for tumor detection.
  • Examination of OCT integration with other imaging modalities (MRI, ultrasound, 5-ALA).

Main Results:

  • OCT provides in vivo, real-time, high-resolution imaging of brain tissue.
  • It enables precise identification of tumor infiltration and blood vessels.
  • Combining OCT with other methods enhances resection accuracy and safety.

Conclusions:

  • OCT significantly improves intraoperative visualization and precision in brain tumor surgery.
  • Its integration with advanced techniques promises theranostic capabilities for automated lesion management.
  • Further development and adoption of OCT can lead to higher precision and intelligence in neuro-oncological procedures.