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Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle

Chan-Hyuk Lee1, Sang Hak Yi2, Byoung-Soo Shin1,3

  • 1Department of Neurology, Jeonbuk National University Medical School and Hospital, Jeonju 54907, Korea.

Diagnostics (Basel, Switzerland)
|February 25, 2022
PubMed

Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.

Keywords:
atrial fibrillationcerebral embolireperfusion injury

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