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Anatomical-MRI Correlations in Adults and Children with Hypertrophic Cardiomyopathy

Radu Ovidiu Rosu1,2, Ana Lupsor2, Alexandru Necula2

  • 1Fifth Department of Internal Medicine, Cardiology Rehabilitation, 400347 Cluj-Napoca, Romania.

Diagnostics (Basel, Switzerland)
|February 25, 2022
PubMed

Insights

Hypertrophic Cardiomyopathy (HCM), a common inherited heart condition, is increasingly diagnosed using Cardiac Magnetic Resonance (CMR) imaging. This review details CMR

Area of Science:

  • Cardiovascular Medicine
  • Medical Imaging
  • Genetics

Background:

  • Hypertrophic Cardiomyopathy (HCM) is the most common inherited cardiovascular disease and a primary cause of sudden cardiac death in young people.
  • Cardiac Magnetic Resonance (CMR) imaging facilitates earlier detection and improved prognostic accuracy for HCM.
  • Future interventions may aim to modify the natural progression of HCM.

Purpose of the Study:

  • To review the magnetic resonance imaging features of Hypertrophic Cardiomyopathy (HCM).
  • To differentiate HCM from other conditions like athlete's heart, hypertension, and infiltrative cardiomyopathies.
  • To discuss HCM in children, including distinct risk factors and the role of delayed enhancement in risk stratification.

Main Methods:

  • Review of existing literature and imaging findings related to CMR in HCM.
  • Analysis of distinct phenotypic variants and differential diagnoses.
  • Focus on specific considerations for pediatric HCM.

Main Results:

  • CMR is a highly sensitive and specific tool for HCM management with minimal risks.
  • Detailed magnetic resonance features of various HCM phenotypes are presented.
  • Delayed enhancement on CMR may be crucial for risk stratification in pediatric HCM.

Conclusions:

  • CMR is a valuable tool for diagnosing and managing Hypertrophic Cardiomyopathy.
  • Understanding CMR features aids in differentiating HCM from other cardiac conditions.
  • Specific considerations for pediatric HCM, including risk stratification, are highlighted.

Keywords:
apical aneurysmcardiac MRIdelayed enhancementhypertrophic cardiomyopathyinterstitial fibrosismyocyte disarraysudden cardiac death

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