Movement Disorders Induced by SARS-CoV-2 Infection: Protocol for a Scoping Review
Elena Cecilia Rosca1,2, Zsolt Vastag3,4, Onanong Phokaewvarangkul5
1Department of Neurology, Victor Babes University of Medicine and Pharmacy of Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Abstract:
Infections are a significant cause of movement disorders. The clinical manifestations of SARS-CoV-2 infection are variable, with up to one-third of patients developing neurologic complications, including movement disorders. This scoping review will lay out a comprehensive understanding of movement disorders induced by SARS-CoV-2 infection. We aim to investigate the epidemiology, clinical and paraclinical features, interventions, and diagnostic challenges in patients with different types of movement disorders in the context of SARS-CoV-2 infection. We will search three databases applying appropriate search terms. Inclusion and exclusion criteria are pre-defined; the data of eligible studies will be extracted in standardized forms. We will report the results following Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). We will present information for clinicians and other healthcare professionals, policymakers, and public health researchers. In addition, the results of the present review may assist in the development and confirmation of inclusion criteria and research questions for further systematic review or meta-analysis, with more precise, narrower questions.
Insights
SARS-CoV-2 infection can cause neurological issues, including movement disorders. This review comprehensively examines these SARS-CoV-2-induced movement disorders, covering their epidemiology, clinical features, and management.
Area of Science:
- Neurology
- Infectious Diseases
- Public Health
Background:
- Infections are a known cause of movement disorders.
- Neurologic complications, including movement disorders, affect up to one-third of patients with SARS-CoV-2 infection.
Purpose of the Study:
- To provide a comprehensive understanding of movement disorders induced by SARS-CoV-2 infection.
- To investigate the epidemiology, clinical and paraclinical features, interventions, and diagnostic challenges associated with these disorders.
Main Methods:
- Scoping review methodology.
- Searches across three databases using predefined inclusion and exclusion criteria.
- Data extraction using standardized forms and reporting following PRISMA-ScR guidelines.
Main Results:
- This section will present synthesized findings on SARS-CoV-2-associated movement disorders.
- Information will be categorized by disorder type, epidemiological data, clinical presentations, and treatment approaches.
Conclusions:
- The review will offer valuable insights for clinicians, healthcare professionals, policymakers, and researchers.
- Findings may inform future systematic reviews and meta-analyses on SARS-CoV-2 and movement disorders.
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