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Music Intervention for Pain Control in the Pediatric Population: A Systematic Review and Meta-Analysis
Berne Ting1,2, Chia-Lin Tsai2,3, Wei-Ti Hsu3,4
1Ph.D. Program for Aging, College of Medicine, China Medical University, Taichung 404, Taiwan.
Insights
Music intervention significantly reduces pain and improves vital signs in infants and children. This meta-analysis confirms music therapy
Area of Science:
- Pediatric Pain Management
- Evidence-Based Complementary Medicine
- Clinical Musicology
Background:
- Music intervention (MI) is recognized for its role in pain management.
- A comprehensive meta-analysis on the analgesic effects of MI in pediatric populations is lacking.
- This study addresses the need for synthesized evidence on music therapy for pain in children.
Purpose of the Study:
- To systematically review and meta-analyze randomized controlled trials (RCTs) evaluating the analgesic efficacy of music intervention in infants and children.
- To assess the impact of music therapy on pain intensity and vital signs in pediatric patients.
- To explore variations in efficacy based on age groups, pain types, and music genres.
Main Methods:
- Systematic literature search of PubMed, EMBASE, Web of Science, and Cochrane Library databases (up to January 2022).
- Inclusion of RCTs investigating music intervention for pain in pediatric populations.
- Meta-analysis using a random-effects model to calculate standardized mean differences (SMDs) and 95% confidence intervals (CIs).
Main Results:
- Music intervention significantly reduced overall pain intensity (SMD = -0.57, p < 0.001) in both newborns and older children.
- MI demonstrated significant reductions in heart rate (SMD = -0.50, p < 0.001) and respiratory rate (SMD = -0.60, p = 0.002), and increased oxygen saturation (SMD = 0.44, p < 0.001).
- Significant analgesic effects were noted for prick, chronic, procedural, and postoperative pain, with classical, kids', and pop music genres showing the most pronounced benefits.
Conclusions:
- Music intervention is an effective adjunctive therapy for managing various types of pain in pediatric patients.
- Specific music genres, including classical, kids', and pop music, are particularly effective in alleviating pain.
- The findings support the integration of music therapy into clinical practice for pediatric pain management.
Abstract:
Music intervention (MI) has been applied as an effective adjunctive treatment for pain control in various clinical settings. However, no meta-analysis has yet been published on the analgesic effects of MI in infants and children. We performed a systematic review of PubMed, EMBASE, Web of Science, and Cochrane Library databases to identify randomized controlled trials (RCTs) with the keywords "pain" AND "music therapy" from inception to January 2022. Primary outcomes were pain intensity and vital signs. Standardized mean difference (SMD) values and the corresponding 95% confidence intervals (CIs) were computed using a random effect model. Subgroup analyses with age groups, types of pain, and music styles were conducted. A total of 38 RCTs involving 5601 participants met the selection criteria. MI significantly decreased the pain levels (SMD = -0.57, p < 0.001), both in the newborn group (p = 0.007) and in the infant/children group (p < 0.001). MI significantly reduced heart rate (SMD = -0.50, p < 0.001) and respiratory rate (SMD = -0.60, p = 0.002) and increased peripheral capillary oxygen saturation (SMD = 0.44, p < 0.001). In subgroup analyses of types of pain, MI had significant effects on prick pain (p = 0.003), chronic and procedural pain (p < 0.001), and postoperative pain (p = 0.018). As for music styles, significant analgesic effects were observed for classical music (p < 0.001), kids' music (p < 0.001), and pop music (p = 0.001), but not for world music (p = 0.196), special composition (p = 0.092), and multiple music combinations (p = 0.420). In conclusion, our analysis provides supportive evidence about the efficacy of MI, especially classical, kids', and pop music, in controlling prick, procedural, and postoperative pain in the pediatric population.
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