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Updated: Oct 2, 2025

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Resveratrol and Reproductive Health
Radmila Novakovic1,2, Jovana Rajkovic1, Milos Gostimirovic1
1Institute of Pharmacology, Medical Faculty, Clinical Pharmacology and Toxicology, University of Belgrade, 11129 Belgrade, Serbia.
Abstract:
Resveratrol (RSV), a plant-derived polyphenol, demonstrates broad-spectrum health benefits, including anti-proliferative, anti-inflammatory, antidiabetic, anti-ischemic and antioxidant effects. The aim of this review is to give an important heads-up regarding the influence of RSV as a phytoestrogen, RSV effects on most common pregnancy-related complications, as well as its impact on the embryogenesis, spermatogenesis, and women's reproductive health. Considering the important implications of RSV on human reproductive health, this overview could provide a groundwork, encouraging more detailed research at the clinical level.
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