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Pharmacogenetics to Avoid Adverse Drug Reactions
1Servicio de Farmacia, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Journal of Personalized Medicine
|February 25, 2022
Summary
Treatments aim for cures but serious adverse reactions pose significant clinical and economic challenges for healthcare systems. Managing these side effects is crucial for patient safety and cost-effectiveness.
Area of Science:
- Pharmacology and Clinical Medicine
- Health Economics
Background:
- Serious adverse reactions (SARs) are a significant obstacle in achieving treatment goals.
- These reactions incur substantial financial burdens on healthcare systems globally.
Discussion:
- The clinical management of SARs requires careful consideration of patient safety and resource allocation.
- Balancing treatment efficacy with the risk of adverse events is a core challenge.
Key Insights:
- Adverse reactions represent a major unmet need in therapeutic development.
- Economic impact of SARs necessitates innovative strategies for mitigation and management.
Outlook:
- Future research should focus on developing safer therapeutics with reduced adverse event profiles.
- Optimizing treatment protocols to minimize SARs is essential for sustainable healthcare.
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