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Drug-Coated Balloons for the Dysfunctional Vascular Access: An Evidence-Based Road Map to Treatment and the Existing

Panagiotis Kitrou1, Konstantinos Katsanos1, Georgia Andriana Georgopoulou2

  • 1Department of Interventional Radiology, Patras University Hospital, Patras, Greece.

Seminars in Interventional Radiology
|February 25, 2022
PubMed

Insights

Drug-coated balloon angioplasty shows promise for treating venous stenosis in hemodialysis access circuits, improving graft and fistula function and reducing swelling. This approach offers a valuable alternative to traditional methods.

Area of Science:

  • Vascular Surgery
  • Interventional Nephrology
  • Medical Devices

Background:

  • Venous stenosis in hemodialysis access circuits is a primary cause of graft and fistula dysfunction.
  • Symptoms include swelling in the arm, breast, and neck.
  • Current treatments include balloon angioplasty and stenting.

Purpose of the Study:

  • To review the current evidence on drug-coated balloon angioplasty for venous stenosis in hemodialysis access circuits.
  • To evaluate the efficacy and safety of this treatment modality.

Main Methods:

  • Review of existing clinical studies and trials.
  • Analysis of data on drug-coated balloon angioplasty outcomes.
  • Comparison with traditional angioplasty and stenting.

Main Results:

  • Drug-coated balloons demonstrate potential in treating venous stenoses.
  • Improved patency rates and reduced re-stenosis observed in some studies.
  • Further research is needed to establish long-term efficacy.

Conclusions:

  • Drug-coated balloon angioplasty is a viable treatment option for hemodialysis access venous stenosis.
  • It may offer advantages over conventional balloon angioplasty.
  • Continued investigation is warranted to optimize its application.

Keywords:
angioplastydrug-coated balloonsinterventional radiologypaclitaxelstenosisvascular access

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