Related Experiment Video
Updated: Oct 2, 2025

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
Published on: December 9, 2016
Intradural Extramedullary Ewing Sarcoma in an Adolescent Female
Mikkel Kunwald1, Christian Lund Straszek2,3,4, Carsten Reidies Bjarkam1
1Department of Neurosurgery, Aalborg University Hospital, Aalborg, Denmark.
A rare pediatric spinal Ewing sarcoma was diagnosed in a 15-year-old female presenting with lumbar pain. Complete surgical resection followed by oncological treatment led to a positive outcome with no long-term sequelae besides hypogonadism.
Area of Science:
- Pediatric Oncology
- Neurosurgery
- Orthopedic Oncology
Background:
- Intradural extramedullary spinal tumors are rare in adolescents.
- Ewing sarcoma is an aggressive bone cancer typically affecting children and young adults.
Observation:
- A 15-year-old female presented with persistent lumbar pain unresponsive to analgesics.
- Magnetic resonance imaging revealed an intradural extramedullary tumor at L3.
- Histopathology confirmed Ewing sarcoma with EWSR1 gene identification.
Findings:
- Complete tumor resection was achieved via neurosurgery.
- The patient received adjuvant photon irradiation therapy and chemotherapy.
- Post-treatment follow-up at 36 months shows a positive prognosis.
Implications:
- This case highlights the importance of considering rare spinal tumors in adolescent lumbar pain.
- Multidisciplinary treatment, including surgery and oncological therapies, is crucial for managing spinal Ewing sarcoma.
- Long-term surveillance is necessary to monitor for potential sequelae such as hypogonadism.
More Related Videos
07:31A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
Published on: May 3, 2021
07:50Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts
Published on: May 25, 2018