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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Young Children Allergic Rhinitis Questionnaire is a novel tool for allergy screening in children
Xiao Xiao1, Guoshuang Feng2, Yawei Zhang3
1Department of Otorhinolaryngology, Head and Neck Surgery, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Insights
A new questionnaire, the Young Children Allergic Rhinitis Questionnaire (YCAR-Q), effectively screens for allergic rhinitis in young children. This validated tool aids in early detection and clinical management of allergic rhinitis in toddlers.
Area of Science:
- Pediatrics
- Allergology
- Clinical Diagnostics
Background:
- Limited validated screening tools exist for allergic rhinitis (AR) in children under three years old.
- Accurate diagnosis of AR in very young children presents clinical challenges.
- Development of reliable screening methods is crucial for early intervention.
Purpose of the Study:
- To develop and validate a novel self-reported questionnaire for allergic rhinitis screening in children aged three years and younger.
- To assess the accuracy and reliability of the developed questionnaire in a clinical setting.
- To provide a practical tool for the early detection of allergic rhinitis in pediatric populations.
Main Methods:
- Expert screening of questionnaire items followed by administration of the Young Children Allergic Rhinitis Questionnaire (YCAR-Q) to a birth cohort.
- Electronic distribution of the YCAR-Q via online communities and physician examinations for diagnosis.
- Evaluation of internal consistency, content validity, criterion-related validity, and diagnostic accuracy using established statistical methods.
Main Results:
- A six-item YCAR-Q was distributed to 7423 parents, with 3037 valid responses.
- Physician examinations confirmed allergic rhinitis in 82 out of 1521 children.
- The YCAR-Q demonstrated good internal consistency (Cronbach's alpha = 0.777) and diagnostic accuracy (AUC = 0.759) with a cutoff score of 3 (sensitivity 68.29%, specificity 76.58%).
Conclusions:
- The YCAR-Q is a reliable and accurate tool for detecting allergic rhinitis in children three years and younger.
- This brief questionnaire can be effectively utilized in clinical practice for screening purposes.
- The YCAR-Q facilitates early identification and management of allergic rhinitis in a vulnerable pediatric age group.
Background:
There are a limited number of validated questionnaires available for use in the clinical screening for allergic rhinitis (AR) in children ≤3 years old. We developed a novel self-reported questionnaire and assessed its accuracy and reliability.
Methods:
After establishing a pool of items, which were screened by experts, the Young Children Allergic Rhinitis Questionnaire (YCAR-Q) was administered to a birth cohort in the Shunyi District (Beijing, China). The electronic version of the YCAR-Q was distributed through the online community. Children were invited to visit a physician for examination. The diagnostic criteria included symptoms, physical examination findings, and specific serum immunoglobulin E tests. Each item on the questionnaire was evaluated, and the questionnaire's internal consistency, content validity, criterion-related validity, and diagnostic accuracy were assessed.
Results:
The six-item YCAR-Q was distributed to 7423 parents, and 3037 valid questionnaires were recovered. In total, 1521 children visited a physician for examination, of which 82 were found to have AR. In terms of internal consistency, Cronbach's coefficient was 0.777 and all six questionnaire items were retained. The average scale-level content validity index value was 1. The area under the curve was 0.759. The total scores ranged from 0 to 6, and the cutoff value for diagnosing AR was 3, with a sensitivity of 68.29% and a specificity of 76.58%.
Conclusions:
This cross-sectional study indicated that the YCAR-Q could detect AR in children ≤3 years old. This brief and simple test may be used effectively in clinical practice.
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