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Sample Preparation and Imaging of Exosomes by Transmission Electron Microscopy
Published on: January 4, 2018
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Inflammasome-Derived Exosomes Isolation and Imaging by Transmission Electron Microscopy
1State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Methods in Molecular Biology (Clifton, N.J.)
|February 25, 2022
Abstract:
Exosomes are secreted small vesicles with diameters of 30-150 nm from cells. These vesicles transfer protein, mRNA, and miRNA to recipient cells to mediate many biological processes, including tumorigenesis, metastasis, drug resistance, immune response, etc. Here we describe the isolation and imaging of NLRP3 inflammasome-derived exosomes by transmission electron microscopy.

