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Updated: Oct 2, 2025

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
Published on: March 13, 2018
Experimental Nuclear Medicine Meets Tumor Biology
Theresa Balber1,2, Loan Tran1, Katarína Benčurová1,2
1Ludwig Boltzmann Institute Applied Diagnostics, 1090 Vienna, Austria.
Abstract:
Personalized treatment of cancer patients demands specific and validated biomarkers for tumor diagnosis and therapy. The development and validation of such require translational preclinical models that recapitulate human diseases as accurately as possible. Moreover, there is a need for convergence of different (pre)clinical disciplines that openly share their knowledge and methodologies. This review sheds light on the differential perception of biomarkers and gives an overview of currently used models in tracer development and approaches for biomarker discovery.
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