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Fertility Considerations in Hypogonadal Men.
Nikoleta Papanikolaou1, Rong Luo1, Channa N Jayasena1
1Section of Investigative Medicine Imperial College London, Hammersmith Hospital, 6th Floor, Commonwealth Building, 150 Du Cane Road, London W12 0NN, UK.
Endocrinology and Metabolism Clinics of North America
|February 26, 2022
Summary
Hypogonadism affects up to 40% of infertile men, impairing sperm production. Treatment varies by onset and cause, with assisted reproduction as a last resort for male infertility.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Andrology
Background:
- Hypogonadism affects up to 40% of men with couple infertility.
- Testosterone is crucial for spermatogenesis; its deficiency impairs fertility.
- The impact of hypogonadism on fertility depends on onset timing and semen parameters.
Purpose of the Study:
- To review the impact of hypogonadism on male fertility.
- To discuss treatment strategies for hypogonadism in infertile men.
- To highlight the role of assisted reproductive technologies.
Main Methods:
- Literature review of hypogonadism and male infertility.
- Analysis of clinical impact based on onset and semen parameters.
- Overview of treatment pathways and success rates.
Main Results:
- Hypogonadism is a significant factor in male subfertility.
- Fertility potential is influenced by the timing of hypogonadism onset.
- Treatment efficacy varies, necessitating consideration of assisted reproduction.
Conclusions:
- Hypogonadism significantly impacts male fertility potential.
- Tailored treatment approaches are essential for managing hypogonadism-related infertility.
- Assisted reproductive technologies offer solutions when medical treatments are insufficient.
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