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Outcomes of surgical treatment for active infective endocarditis under COVID-19 pandemic
XinPei Liu1, Qi Miao2, XingRong Liu1
1Department of Cardiac Surgery, Peking Union Medical College Hospital, Dongcheng District, Beijing, China.
Insights
The COVID-19 pandemic impacted infective endocarditis (IE) diagnosis and treatment, leading to more emergency admissions and severe conditions. However, multidisciplinary teams maintained comparable early surgical outcomes for IE patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Treatment
Background:
- The COVID-19 pandemic presented significant challenges to global healthcare systems.
- Surgical treatment for active infective endocarditis (IE) requires careful management, potentially disrupted by pandemic-related issues.
Purpose of the Study:
- To analyze the impact of the COVID-19 pandemic on the diagnosis, timing, and prognosis of surgical treatment for active IE.
- To share strategies for managing IE surgical care during the pandemic.
Main Methods:
- Retrospective analysis of 39 patients admitted for active IE in 2020 (pandemic year) compared to 50 patients from the previous year.
- Data extracted from a surgical database, comparing patient demographics, clinical presentation, surgical risk, and outcomes.
Main Results:
- Fewer transferred patients admitted (64.1% vs. 80%), prolonged diagnosis times (60 vs. 34.5 days), and increased emergency admissions (41% vs. 20%).
- Higher incidence of heart failure (74.4% vs. 40%), sepsis (69.2% vs. 42.0%), and cardiogenic shock (25.6% vs. 8.0%) during the pandemic.
- Increased surgical risk (EuroSCORE II: 4.15% vs. 3.24%), yet no significant increase in postoperative complications or early mortality (0% vs. 4%).
Conclusions:
- The COVID-19 pandemic had multifaceted negative impacts on the clinical practice of surgical IE treatment.
- Effective multidisciplinary IE surgical teams ensured that early outcomes remained comparable to pre-pandemic levels.
Background:
The coronavirus disease 2019 (COVID-19) pandemic has been and will continue to be a challenge to the healthcare system worldwide. In this context, we aimed to discuss the impact of the COVID-19 pandemic on the diagnosis, timing, and prognosis of surgical treatment for active infective endocarditis (IE) during the pandemic and share our coping strategy.
Methods:
A total of 39 patients were admitted for active IE in the year 2020. The number of the same period last year was 50. Medical information of these two groups was extracted from our surgical database. Data were compared between the two groups and differences with or without statistical significance were discussed.
Results:
In the pandemic year, we admitted fewer transferred patients (64.1% vs. 80%, p = .094). Timespan for diagnosis were prolonged (60 vs. 34.5 days, p = .081). More patients were admitted in emergency (41% vs. 20%, p = .030) More patients had heart failure (74.4% vs. 40%, p = .001), sepsis (69.2% vs. 42.0%, p = .018), or cardiogenic shock (25.6% vs. 8.0%, p = .038). Overall surgical risk (EuroSCORE II) was higher (4.15% vs. 3.24%, p = .019) and more commando surgery was performed (7.7% vs. 2.0%, p = .441). However, we did not see more postoperative complications, and early mortality was not worse either (0 vs. 4%, p = .502).
Conclusions:
The negative impact of the COVID-19 pandemic on the clinical practice of surgical treatment for active IE was multifaceted. However, with the preservation of the effectiveness of multidisciplinary IE surgical team, the early outcomes were comparable with those in the normal years.
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