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Updated: Oct 2, 2025
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Synthesis and physicochemical characteristics of Ag-doped hydroxyapatite nanoparticles, and their potential
Saleth Sebastiammal1, Arul Sigamani Lesly Fathima1, Saud Alarifi2
1Research Department of Physics, Holy Cross College (Autonomous), Nagercoil, 629004, Tamil Nadu, India; Affiliated to Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli, 627012, Tamil Nadu, India.
Abstract:
In this present scenario, hydroxyapatite (HAp) nanostructures were synthesized through green routes for biomedical applications, particularly remediation towards human pathogens and cancer cells. The present study aims at forming non-toxic and eco-friendly silver (Ag+) doped HAp using Polyethylene glycol (PEG), Cetyl Trimethyl ammonium bromide (CTAB) and curcumin. Ag+ doped HAp nanoparticles (NPs) were prepared by the sol-gel method with a cube and rod-like morphology. Ag-HApNPs showed a sharp and well-defined diffraction peak, which possesses the hexagonal crystalline structure with space group P63/m. The Fourier-transform infrared spectroscopy and Raman spectra confirmed the formation of Ag-HApNPs, and the bandgap values were obtained using UV-DRS analysis. The Ag-HApNPs with PEG, CTAB and curcumin might be fabricated materials were examined against antibacterial, antifungal, antioxidant, and cytotoxic activities, which provided exemplary biomedical applications. Overall, Ag-HApNPs can be used as potential drug delivery and perspectives to control multidrug-resistant pathogens.
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