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Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity

Connor A Tsuchida1, Shouyue Zhang2, Mohammad Saffari Doost3

  • 1University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, California 94720, USA; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.

Molecular Cell
|February 27, 2022
PubMed

Keywords:
CRISPRCas12eCasXDNA cleavageRNA-guided DNA nucleasecryo-EMgenome editingnucleic acid manipulationsgRNAstructural engineering

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