Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physiologic changes in older skin.

G L Grove

    Dermatologic Clinics
    |July 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Aging skin loses its barrier function, increasing vulnerability to environmental damage. Cutaneous clues can indicate an individual's physiological age, distinct from their chronological age.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Impact of microwave thermolysis energy levels on patient-reported outcomes for axillary hyperhidrosis and osmidrosis.

    Lasers in surgery and medicine·2022
    Same author

    Sustained improvement of surgical scar appearance 1 year after early intervention with nonablative fractional laser treatment: a randomized controlled split-wound trial.

    The British journal of dermatology·2020
    Same author

    A refined method to evaluate diapers for effectiveness in reducing skin hydration using the adult forearm.

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2016
    Same author

    An RCT on the effects of topical CGP on surgical wound appearance and residual scarring in bilateral total-knee arthroplasty patients.

    Journal of wound care·2012
    Same author

    Scrotal temperatures do not differ among young boys wearing disposable or reusable diapers.

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2002
    Same author

    Methods for evaluating changes in skin condition due to the effects of antimicrobial hand cleansers: two studies comparing a new waterless chlorhexidine gluconate/ethanol-emollient antiseptic preparation with a conventional water-applied product.

    American journal of infection control·2001

    Area of Science:

    • Gerontology
    • Dermatology
    • Physiology

    Background:

    • The skin's protective barrier function declines with age.
    • Elderly individuals are more susceptible to environmental insults due to reduced barrier function and delayed reactions.
    • Impaired skin barrier leads to accumulation of irritants, potentially causing chronic dermatitis.

    Purpose of the Study:

    • To investigate the relationship between aging and skin barrier function.
    • To identify cutaneous markers of physiological aging.
    • To explore the implications of age-related skin changes in the elderly population.

    Main Methods:

    • Observational studies on skin aging.
    • Analysis of stratum corneum barrier function in elderly individuals.

    Related Experiment Videos

  • Assessment of integumental reactions and clearance of noxious substances.

    • Main Results:

    • The stratum corneum's barrier capacity diminishes with age.
    • Reduced barrier function delays the clearance of and reaction to environmental irritants.
    • Accumulation of irritants can exceed thresholds for clinical manifestation in older adults.
    • Slower cellular turnover and repair prolong recovery time from skin damage.

    Conclusions:

    • Cutaneous signs serve as indicators of an individual's physiological age.
    • There can be a significant difference between chronological and physiological age.
    • The skin and its appendages offer valuable markers for monitoring physiological aging in gerontology research.