Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drug-induced fever.

P A Tabor

    Drug Intelligence & Clinical Pharmacy
    |June 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Drug-induced fever, often a hypersensitivity reaction, typically appears 7-10 days after medication initiation. It resolves upon drug discontinuation and recurs upon re-administration.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Antibiotic-related bleeding disorders.

    Focus on critical care·1985
    Same journal

    Profile of prescription medication in a pediatric population.

    Drug intelligence & clinical pharmacy·1988
    Same journal

    SI units in drug therapeutics.

    Drug intelligence & clinical pharmacy·1988
    Same journal

    Physicians' review of significant interventions by clinical pharmacists in inpatient care.

    Drug intelligence & clinical pharmacy·1988
    Same journal

    Possible interaction of ranitidine with phenytoin.

    Drug intelligence & clinical pharmacy·1988
    Same journal

    Famotidine-associated mental confusion in elderly patients.

    Drug intelligence & clinical pharmacy·1988
    Same journal

    Intravenous self-administration of elemental mercury: efficacy of dimercaprol therapy.

    Drug intelligence & clinical pharmacy·1988
    See all related articles

    Area of Science:

    • Pharmacology
    • Immunology
    • Internal Medicine

    Background:

    • Maintaining a narrow body temperature range is crucial for human homeostasis.
    • Drug administration can disrupt thermoregulation, leading to fever.
    • Fever can result from direct drug effects or indirect responses like immune activation.

    Purpose of the Study:

    • To elucidate the mechanisms and characteristics of drug-induced fever.
    • To identify common drug culprits associated with fever.
    • To differentiate drug-induced fever from other febrile conditions.

    Main Methods:

    • Review of pharmacological mechanisms of drug-induced fever.
    • Analysis of clinical presentation and timing of drug-induced fever.
    • Identification of frequently implicated drug classes.

    Related Experiment Videos

    Main Results:

    • Drug-induced fever commonly stems from hypersensitivity reactions, mimicking allergic responses.
    • Fever typically emerges 7-10 days into drug therapy.
    • Fever resolution occurs upon drug cessation and rapid recurrence upon re-challenge.

    Conclusions:

    • Drug-induced fever is a significant adverse drug reaction.
    • Hypersensitivity is the most frequent cause, characterized by specific temporal patterns.
    • Commonly implicated drugs include penicillins, cephalosporins, and certain cardiovascular agents.