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Acute Myocardial Infarction After Coronavirus Vaccine: A Rare Adverse Effect

Sameen Iqbal1, Ghufran Adnan1, Awais Farhad1

  • 1Cardiology, Aga Khan University, Karachi, PAK.

Cureus
|February 28, 2022
PubMed

Insights

A man experienced acute coronary syndrome after his first Moderna COVID-19 vaccine dose. While rare, this highlights the need for vigilance and monitoring of vaccine side effects.

Area of Science:

  • Cardiology
  • Immunology
  • Vaccinology

Background:

  • The global rollout of coronavirus disease 2019 (COVID-19) vaccines aims to curb the pandemic.
  • Understanding potential adverse events following immunization is crucial for public health.
  • Pre-existing conditions may influence vaccine response and risk of adverse events.

Observation:

  • A 61-year-old male with ischemic heart disease developed acute coronary syndrome (ACS).
  • Symptoms of left arm and jaw pain began 90 minutes post-Moderna COVID-19 vaccination.
  • The patient was diagnosed with non-ST-elevation myocardial infarction.

Findings:

  • Percutaneous coronary intervention was performed successfully.
  • The patient was discharged after a two-day hospital stay and was clinically stable.
  • The temporal association suggests a possible link between the COVID-19 vaccine and the ACS event in this high-risk individual.

Implications:

  • Healthcare providers must be aware of potential rare vaccine side effects.
  • Further investigation and risk assessment may be warranted for high-risk patients before vaccination.
  • Continued monitoring of vaccine safety data is essential to prevent future adverse events and maintain public confidence in vaccination programs.

Keywords:
acutecovid-19modernamyocardial infarctionvaccine

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