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Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
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Anterior cervical spine surgery opens up concerns about thyroid function.

Kaveh Haddadi1, Saeed Heidarpour Khanghah2, Siavash Moradi3

  • 1Department of Neurosurgery, Orthopedics Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Biomedicine
|February 28, 2022
PubMed
Summary

Anterior cervical spine surgery did not reveal significant thyroid hormone changes. However, age correlated with thyroid-stimulating hormone (TSH) changes, suggesting pre-operative thyroid screening, especially for older adults undergoing spinal procedures.

Keywords:
ACDFAnterior cervicalDiscectomy and FusionThyroid dysfunction

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Area of Science:

  • Neurosurgery
  • Endocrinology
  • Degenerative Spine Disease

Background:

  • Anterior cervical spine surgery is crucial for spinal cord decompression and stabilization.
  • Thyroid complications are well-documented in other neck surgeries but understudied in anterior cervical spine procedures.
  • This study investigates potential thyroid changes following anterior cervical approaches for degenerative conditions.

Purpose of the Study:

  • To evaluate thyroid function alterations in patients undergoing anterior cervical spine surgery.
  • To identify any correlation between surgical factors and thyroid hormone changes.
  • To assess the impact of anterior cervical spine surgery on thyroid health.

Main Methods:

  • Seventy patients undergoing anterior cervical spine surgery were enrolled.
  • Demographic data and medical records were collected.
  • Thyroid hormones (TSH, free T4, free T3) were measured pre-operatively and three months post-operatively.

Main Results:

  • Cervical disc herniation was the most common diagnosis (60%).
  • No significant correlation was found between TSH changes and surgical variables (levels, duration, incision type, surgery type).
  • A significant positive correlation was observed between TSH changes and patient age.

Conclusions:

  • Anterior cervical spine surgery did not demonstrate functional thyroid tissue injury.
  • Age-related laboratory changes and rare case reports suggest caution.
  • Pre-operative thyroid function tests are recommended for patients with degenerative cervical diseases, particularly older adults.