Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced DVT Prevention in Non-ICU Medical Patients: a Cohort Study of IPC Plus LMWH vs. LMWH Alone.

Clinical laboratory·2026
Same author

Janus barrier films of shellac/chitosan with natamycin for photoprotective on-demand antifungal release and starch metabolism regulation in kiwifruit preservation.

Food research international (Ottawa, Ont.)·2026
Same author

Mechanical movements generated by movable lipids break endosomal barriers for enhanced mRNA therapeutics.

Science advances·2026
Same author

Assessing the efficacy and ecological impact of a plastic-dissolving agent on microplastic removal and soil microbial communities.

Ecotoxicology and environmental safety·2026
Same author

Sequential targeting nanochaperone disrupts positive feedback loop of mitochondrial dysfunction for Alzheimer's disease therapy.

Biomaterials·2026
Same author

Computed tomography findings and severity scores in Chlamydia psittaci pneumonia: a retrospective study of 69 cases with clinical correlation.

BMC infectious diseases·2026

Related Experiment Video

Updated: Oct 2, 2025

Decellularization and Recellularization of Whole Livers
09:24

Decellularization and Recellularization of Whole Livers

Published on: February 4, 2011

22.2K

Recent Advances in Liver Engineering With Decellularized Scaffold.

Qingqing Dai1,2, Wei Jiang3, Fan Huang1

  • 1Department of Hepatopancreatobiliary Surgery and Organ Transplantation Center, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Frontiers in Bioengineering and Biotechnology
|February 28, 2022
PubMed
Summary
This summary is machine-generated.

Decellularized liver scaffolds offer a promising solution to donor liver shortages. This review explores their potential for creating transplantable bioengineered livers through recellularization.

Keywords:
decellularizationimplantationliver engineeringrecellularizationscaffold

More Related Videos

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.2K
A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat
13:27

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

Published on: October 6, 2018

8.2K

Related Experiment Videos

Last Updated: Oct 2, 2025

Decellularization and Recellularization of Whole Livers
09:24

Decellularization and Recellularization of Whole Livers

Published on: February 4, 2011

22.2K
Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.2K
A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat
13:27

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

Published on: October 6, 2018

8.2K

Area of Science:

  • Regenerative Medicine
  • Tissue Engineering
  • Hepatology

Background:

  • End-stage liver disease necessitates transplantation, but donor organ scarcity is a critical limitation.
  • Bioengineering strategies are crucial for developing alternative liver sources.
  • Decellularized liver scaffolds are emerging as a viable option for liver regeneration.

Purpose of the Study:

  • To review the current state of decellularized liver scaffolds for transplantation.
  • To discuss the processes of decellularization and recellularization in liver engineering.
  • To cover assessment criteria and challenges in scaffold utilization.

Main Methods:

  • Review of existing literature on liver decellularization and recellularization techniques.
  • Analysis of the structural and biochemical properties of decellularized liver scaffolds.
  • Examination of recent advancements and challenges in the field.

Main Results:

  • Decellularized scaffolds retain the native liver architecture and extracellular matrix.
  • Recellularization holds the potential to generate a functional, transplantable liver graft.
  • Significant progress has been made, but challenges remain in clinical application.

Conclusions:

  • Decellularized liver scaffolds represent a promising approach to address donor organ shortages.
  • Further research is needed to optimize recellularization and overcome clinical hurdles.
  • This technology has the potential to revolutionize liver transplantation.